@article{10.11648/j.sjph.20150305.25,
  author = {Bassey Enya Bassey and Alex Gasasira and Goitom Weldegbriel and Maleghemi Toritseju Sylvester and Koko I. Richard and Igbu Thompson and Ayodele Benjamin and Sylvester Agwai and Godwin Ubong Akpan},
  title = {Impact of a Nationwide Measles Immunization Campaign and Routine Immunization in Nigeria, 2006-2010: A Critical Review of South-South, Nigeria},
  journal = {Science Journal of Public Health},
  volume = {3},
  number = {5},
  pages = {693-698},
  doi = {10.11648/j.sjph.20150305.25},
  url = {https://doi.org/10.11648/j.sjph.20150305.25},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjph.20150305.25},
  abstract = {Background: Measles remains a serious problem of infancy and childhood in the developing world, despite the availability of vaccine. Increasing urbanization is changing patterns of endemicity. Objective: This paper critically examines the epidemiological impact of this nationwide measles immunization campaign and routine immunization, while taking into account any changes in surveillance performance. Methods: Blood samples were obtained from 4159 client at the surveillance focal sites scattered across the 123 district (LGAs) and were tested for measles specific immunoglobulin M (IgM). Five (5) ml of blood was collected from each subject into plain sterile bottle following informed consent. Blood samples were centrifuged and sera were separated and stored at -20oC until used. Samples were analyzed in batches for measles specific IgM using commercial ELISA (MV-ELISA) (Enzygnost; Behring Diagnostics, Marburg, Germany) in accordance with the manufacturer’s instructions. Tests were read on a pre-programmed spectrophotometer Quantum II, wavelength 450/630nm, manufactured by Abbott. Results: In total, 465 (11.2%) tested positive for measles specific IgM antibodies. Of these, 1962 were male and 2197 were female. The highest number of IgM positive cases was found in those less than 5 years (79.8%), while those aged 5-15 years, and 15 years and above recorded 17.2% and 3.0% respectively. The distribution of measles burden between urban and rural setting indicates that urban dwellers 53.8% were more susceptible to measles than rural dwellers (46.2%), this relationship was established as statistically significant with (p< 0.0001) and odds ratio was also high 1.669 (95% CI 1.375-2.025). A high significance of association between development of measles and vaccination status of subjects is also observed in this study (p < 0.0001), while odds ratio was also observed to be high 6.144 (95% CI 4.977-7.511). Conclusions: Improved understanding of measles epidemiology and risk factors are prerequisites for effective control. Possible strategies should include vertical vaccination efforts in addition to routine programmes.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Impact of a Nationwide Measles Immunization Campaign and Routine Immunization in Nigeria, 2006-2010: A Critical Review of South-South, Nigeria
AU  - Bassey Enya Bassey
AU  - Alex Gasasira
AU  - Goitom Weldegbriel
AU  - Maleghemi Toritseju Sylvester
AU  - Koko I. Richard
AU  - Igbu Thompson
AU  - Ayodele Benjamin
AU  - Sylvester Agwai
AU  - Godwin Ubong Akpan
Y1  - 2015/07/31
PY  - 2015
N1  - https://doi.org/10.11648/j.sjph.20150305.25
DO  - 10.11648/j.sjph.20150305.25
T2  - Science Journal of Public Health
JF  - Science Journal of Public Health
JO  - Science Journal of Public Health
SP  - 693
EP  - 698
PB  - Science Publishing Group
SN  - 2328-7950
UR  - https://doi.org/10.11648/j.sjph.20150305.25
AB  - Background: Measles remains a serious problem of infancy and childhood in the developing world, despite the availability of vaccine. Increasing urbanization is changing patterns of endemicity. Objective: This paper critically examines the epidemiological impact of this nationwide measles immunization campaign and routine immunization, while taking into account any changes in surveillance performance. Methods: Blood samples were obtained from 4159 client at the surveillance focal sites scattered across the 123 district (LGAs) and were tested for measles specific immunoglobulin M (IgM). Five (5) ml of blood was collected from each subject into plain sterile bottle following informed consent. Blood samples were centrifuged and sera were separated and stored at -20oC until used. Samples were analyzed in batches for measles specific IgM using commercial ELISA (MV-ELISA) (Enzygnost; Behring Diagnostics, Marburg, Germany) in accordance with the manufacturer’s instructions. Tests were read on a pre-programmed spectrophotometer Quantum II, wavelength 450/630nm, manufactured by Abbott. Results: In total, 465 (11.2%) tested positive for measles specific IgM antibodies. Of these, 1962 were male and 2197 were female. The highest number of IgM positive cases was found in those less than 5 years (79.8%), while those aged 5-15 years, and 15 years and above recorded 17.2% and 3.0% respectively. The distribution of measles burden between urban and rural setting indicates that urban dwellers 53.8% were more susceptible to measles than rural dwellers (46.2%), this relationship was established as statistically significant with (p< 0.0001) and odds ratio was also high 1.669 (95% CI 1.375-2.025). A high significance of association between development of measles and vaccination status of subjects is also observed in this study (p < 0.0001), while odds ratio was also observed to be high 6.144 (95% CI 4.977-7.511). Conclusions: Improved understanding of measles epidemiology and risk factors are prerequisites for effective control. Possible strategies should include vertical vaccination efforts in addition to routine programmes.
VL  - 3
IS  - 5
ER  - 

Copy | Download