Association Between Prostatic Volume, Metabolic Syndrome and Left Ventricular Mass: A Cross Sectional Study

Ebenezer Adekunle Ajayi; Patrick Temi Adegun; Ganiyu Olusola Akanbi; Akande Oladimeji Ajayi; Peter Olufemi Areo; Felix Olukayode Aina; Samuel Ayokunle Dada

doi:doi:10.11648/j.cmr.20170604.11

Association Between Prostatic Volume, Metabolic Syndrome and Left Ventricular Mass: A Cross Sectional Study

Ebenezer Adekunle Ajayi, Patrick Temi Adegun, Ganiyu Olusola Akanbi, Akande Oladimeji Ajayi, Peter Olufemi Areo, Felix Olukayode Aina, Samuel Ayokunle Dada

Published in Clinical Medicine Research (Volume 6, Issue 4)

Received: 11 April 2017 Accepted: 20 April 2017 Published: 1 June 2017

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Abstract

Ageing in men is associated with increased prevalence of cardiovascular risk factors and benign prostatic hyperplasia (BPH) with both entities possibly representing downstream manifestations of a common pathogenesis. There is paucity of data on the association of BPH and left ventricular hypertrophy (LVH). This study evaluated relationship between prostate volume, common cardiovascular risk factors and LVH. It was a cross sectional, prospective, hospital-based study. Thirty patients with benign prostatic enlargement (BPE) and 30 age- matched male controls without BPE were studied. All the subjects had clinical, biochemical, prostate ultrasound and echocardiographic evaluation done. SPSS IBM 20 was used to analyze data. Mean age was 65.60 ± 8.11 years (range: 54-82years). Subjects with BPE compared to those without did not significantly differ in age (66.50± 7.75 vs. 64.70±8.49; p=0.39). Significantly higher percentage of subjects with BPE had abnormally low HDL-cholesterol and high blood pressure compared with subjects without BPE. Eight (26.7%) of subjects with BPE in contrast to none of the subjects without BPE had metabolic syndrome (Chi2 = 9.231; p=0.002). Left ventricular mass index were significantly higher in subjects with BPE than in those without. None of the subjects without BPE as compared with 7 (23.3%) of subjects with BPE had echocardiographic determined LVH. Echocardiographic indices that significantly correlated with prostatic volume were: LVPWd (r=0.326, p= 0.011), IVSTd (r= 0.267, p=0.039), LVMI(r=0.308, p= 0.017), LAD (r= 0.494, p <0.0001) and AOD (r= 0.352, p= 0.006). The conclusion was that BPE is associated with increased left ventricular mass index and metabolic syndrome, mostly driven by elevated blood pressure and low serum HDL-cholesterol.

Published in	Clinical Medicine Research (Volume 6, Issue 4)
DOI	10.11648/j.cmr.20170604.11
Page(s)	121-126
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Benign Prostatic Hypertrophy, Prostatic Volume, Left Ventricular Hypertrophy, Metabolic Syndrome, Left Ventricular Mass Index

References

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[4]	Madersbacher S, Alivizatos G, Nordling J, Sanz CR, Emberton M, de la Rosette JJ. EAU 2004 guidelines on assessment, therapy and follow-up of men with lower urinary tract symptoms suggestive of benign prostatic obstruction (BPH guidelines). EurUrol 2004; 46:547–54.
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APA Style

Ebenezer Adekunle Ajayi, Patrick Temi Adegun, Ganiyu Olusola Akanbi, Akande Oladimeji Ajayi, Peter Olufemi Areo, et al. (2017). Association Between Prostatic Volume, Metabolic Syndrome and Left Ventricular Mass: A Cross Sectional Study. Clinical Medicine Research, 6(4), 121-126. https://doi.org/10.11648/j.cmr.20170604.11

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ACS Style

Ebenezer Adekunle Ajayi; Patrick Temi Adegun; Ganiyu Olusola Akanbi; Akande Oladimeji Ajayi; Peter Olufemi Areo, et al. Association Between Prostatic Volume, Metabolic Syndrome and Left Ventricular Mass: A Cross Sectional Study. Clin. Med. Res. 2017, 6(4), 121-126. doi: 10.11648/j.cmr.20170604.11

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AMA Style

Ebenezer Adekunle Ajayi, Patrick Temi Adegun, Ganiyu Olusola Akanbi, Akande Oladimeji Ajayi, Peter Olufemi Areo, et al. Association Between Prostatic Volume, Metabolic Syndrome and Left Ventricular Mass: A Cross Sectional Study. Clin Med Res. 2017;6(4):121-126. doi: 10.11648/j.cmr.20170604.11

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@article{10.11648/j.cmr.20170604.11,
  author = {Ebenezer Adekunle Ajayi and Patrick Temi Adegun and Ganiyu Olusola Akanbi and Akande Oladimeji Ajayi and Peter Olufemi Areo and Felix Olukayode Aina and Samuel Ayokunle Dada},
  title = {Association Between Prostatic Volume, Metabolic Syndrome and Left Ventricular Mass: A Cross Sectional Study},
  journal = {Clinical Medicine Research},
  volume = {6},
  number = {4},
  pages = {121-126},
  doi = {10.11648/j.cmr.20170604.11},
  url = {https://doi.org/10.11648/j.cmr.20170604.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20170604.11},
  abstract = {Ageing in men is associated with increased prevalence of cardiovascular risk factors and benign prostatic hyperplasia (BPH) with both entities possibly representing downstream manifestations of a common pathogenesis. There is paucity of data on the association of BPH and left ventricular hypertrophy (LVH). This study evaluated relationship between prostate volume, common cardiovascular risk factors and LVH. It was a cross sectional, prospective, hospital-based study. Thirty patients with benign prostatic enlargement (BPE) and 30 age- matched male controls without BPE were studied. All the subjects had clinical, biochemical, prostate ultrasound and echocardiographic evaluation done. SPSS IBM 20 was used to analyze data. Mean age was 65.60 ± 8.11 years (range: 54-82years). Subjects with BPE compared to those without did not significantly differ in age (66.50± 7.75 vs. 64.70±8.49; p=0.39). Significantly higher percentage of subjects with BPE had abnormally low HDL-cholesterol and high blood pressure compared with subjects without BPE. Eight (26.7%) of subjects with BPE in contrast to none of the subjects without BPE had metabolic syndrome (Chi2 = 9.231; p=0.002). Left ventricular mass index were significantly higher in subjects with BPE than in those without. None of the subjects without BPE as compared with 7 (23.3%) of subjects with BPE had echocardiographic determined LVH. Echocardiographic indices that significantly correlated with prostatic volume were: LVPWd (r=0.326, p= 0.011), IVSTd (r= 0.267, p=0.039), LVMI(r=0.308, p= 0.017), LAD (r= 0.494, p <0.0001) and AOD (r= 0.352, p= 0.006). The conclusion was that BPE is associated with increased left ventricular mass index and metabolic syndrome, mostly driven by elevated blood pressure and low serum HDL-cholesterol.},
 year = {2017}
}

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TY  - JOUR
T1  - Association Between Prostatic Volume, Metabolic Syndrome and Left Ventricular Mass: A Cross Sectional Study
AU  - Ebenezer Adekunle Ajayi
AU  - Patrick Temi Adegun
AU  - Ganiyu Olusola Akanbi
AU  - Akande Oladimeji Ajayi
AU  - Peter Olufemi Areo
AU  - Felix Olukayode Aina
AU  - Samuel Ayokunle Dada
Y1  - 2017/06/01
PY  - 2017
N1  - https://doi.org/10.11648/j.cmr.20170604.11
DO  - 10.11648/j.cmr.20170604.11
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 121
EP  - 126
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20170604.11
AB  - Ageing in men is associated with increased prevalence of cardiovascular risk factors and benign prostatic hyperplasia (BPH) with both entities possibly representing downstream manifestations of a common pathogenesis. There is paucity of data on the association of BPH and left ventricular hypertrophy (LVH). This study evaluated relationship between prostate volume, common cardiovascular risk factors and LVH. It was a cross sectional, prospective, hospital-based study. Thirty patients with benign prostatic enlargement (BPE) and 30 age- matched male controls without BPE were studied. All the subjects had clinical, biochemical, prostate ultrasound and echocardiographic evaluation done. SPSS IBM 20 was used to analyze data. Mean age was 65.60 ± 8.11 years (range: 54-82years). Subjects with BPE compared to those without did not significantly differ in age (66.50± 7.75 vs. 64.70±8.49; p=0.39). Significantly higher percentage of subjects with BPE had abnormally low HDL-cholesterol and high blood pressure compared with subjects without BPE. Eight (26.7%) of subjects with BPE in contrast to none of the subjects without BPE had metabolic syndrome (Chi2 = 9.231; p=0.002). Left ventricular mass index were significantly higher in subjects with BPE than in those without. None of the subjects without BPE as compared with 7 (23.3%) of subjects with BPE had echocardiographic determined LVH. Echocardiographic indices that significantly correlated with prostatic volume were: LVPWd (r=0.326, p= 0.011), IVSTd (r= 0.267, p=0.039), LVMI(r=0.308, p= 0.017), LAD (r= 0.494, p <0.0001) and AOD (r= 0.352, p= 0.006). The conclusion was that BPE is associated with increased left ventricular mass index and metabolic syndrome, mostly driven by elevated blood pressure and low serum HDL-cholesterol.
VL  - 6
IS  - 4
ER  -

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Author Information

Ebenezer Adekunle Ajayi

Department of Medicine, Ekiti State University, Ado Ekiti, Nigeria
Patrick Temi Adegun

Department of Surgery, Ekiti State University, Ado Ekiti, Nigeria
Ganiyu Olusola Akanbi

Department of Radiology, Ekiti State University, Ado Ekiti, Nigeria
Akande Oladimeji Ajayi

Department of Medicine, Ekiti State University, Ado Ekiti, Nigeria
Peter Olufemi Areo

Department of Surgery, Ekiti State University, Ado Ekiti, Nigeria
Felix Olukayode Aina

Department of Family Medicine, Ekiti State University Teaching Hospital, Ado Ekiti, Nigeria
Samuel Ayokunle Dada

Department of Medicine, Ekiti State University, Ado Ekiti, Nigeria

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APA Style

Ebenezer Adekunle Ajayi, Patrick Temi Adegun, Ganiyu Olusola Akanbi, Akande Oladimeji Ajayi, Peter Olufemi Areo, et al. (2017). Association Between Prostatic Volume, Metabolic Syndrome and Left Ventricular Mass: A Cross Sectional Study. Clinical Medicine Research, 6(4), 121-126. https://doi.org/10.11648/j.cmr.20170604.11

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ACS Style

Ebenezer Adekunle Ajayi; Patrick Temi Adegun; Ganiyu Olusola Akanbi; Akande Oladimeji Ajayi; Peter Olufemi Areo, et al. Association Between Prostatic Volume, Metabolic Syndrome and Left Ventricular Mass: A Cross Sectional Study. Clin. Med. Res. 2017, 6(4), 121-126. doi: 10.11648/j.cmr.20170604.11

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AMA Style

Ebenezer Adekunle Ajayi, Patrick Temi Adegun, Ganiyu Olusola Akanbi, Akande Oladimeji Ajayi, Peter Olufemi Areo, et al. Association Between Prostatic Volume, Metabolic Syndrome and Left Ventricular Mass: A Cross Sectional Study. Clin Med Res. 2017;6(4):121-126. doi: 10.11648/j.cmr.20170604.11

Copy | Download

@article{10.11648/j.cmr.20170604.11,
  author = {Ebenezer Adekunle Ajayi and Patrick Temi Adegun and Ganiyu Olusola Akanbi and Akande Oladimeji Ajayi and Peter Olufemi Areo and Felix Olukayode Aina and Samuel Ayokunle Dada},
  title = {Association Between Prostatic Volume, Metabolic Syndrome and Left Ventricular Mass: A Cross Sectional Study},
  journal = {Clinical Medicine Research},
  volume = {6},
  number = {4},
  pages = {121-126},
  doi = {10.11648/j.cmr.20170604.11},
  url = {https://doi.org/10.11648/j.cmr.20170604.11},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cmr.20170604.11},
  abstract = {Ageing in men is associated with increased prevalence of cardiovascular risk factors and benign prostatic hyperplasia (BPH) with both entities possibly representing downstream manifestations of a common pathogenesis. There is paucity of data on the association of BPH and left ventricular hypertrophy (LVH). This study evaluated relationship between prostate volume, common cardiovascular risk factors and LVH. It was a cross sectional, prospective, hospital-based study. Thirty patients with benign prostatic enlargement (BPE) and 30 age- matched male controls without BPE were studied. All the subjects had clinical, biochemical, prostate ultrasound and echocardiographic evaluation done. SPSS IBM 20 was used to analyze data. Mean age was 65.60 ± 8.11 years (range: 54-82years). Subjects with BPE compared to those without did not significantly differ in age (66.50± 7.75 vs. 64.70±8.49; p=0.39). Significantly higher percentage of subjects with BPE had abnormally low HDL-cholesterol and high blood pressure compared with subjects without BPE. Eight (26.7%) of subjects with BPE in contrast to none of the subjects without BPE had metabolic syndrome (Chi2 = 9.231; p=0.002). Left ventricular mass index were significantly higher in subjects with BPE than in those without. None of the subjects without BPE as compared with 7 (23.3%) of subjects with BPE had echocardiographic determined LVH. Echocardiographic indices that significantly correlated with prostatic volume were: LVPWd (r=0.326, p= 0.011), IVSTd (r= 0.267, p=0.039), LVMI(r=0.308, p= 0.017), LAD (r= 0.494, p <0.0001) and AOD (r= 0.352, p= 0.006). The conclusion was that BPE is associated with increased left ventricular mass index and metabolic syndrome, mostly driven by elevated blood pressure and low serum HDL-cholesterol.},
 year = {2017}
}

Copy | Download

TY  - JOUR
T1  - Association Between Prostatic Volume, Metabolic Syndrome and Left Ventricular Mass: A Cross Sectional Study
AU  - Ebenezer Adekunle Ajayi
AU  - Patrick Temi Adegun
AU  - Ganiyu Olusola Akanbi
AU  - Akande Oladimeji Ajayi
AU  - Peter Olufemi Areo
AU  - Felix Olukayode Aina
AU  - Samuel Ayokunle Dada
Y1  - 2017/06/01
PY  - 2017
N1  - https://doi.org/10.11648/j.cmr.20170604.11
DO  - 10.11648/j.cmr.20170604.11
T2  - Clinical Medicine Research
JF  - Clinical Medicine Research
JO  - Clinical Medicine Research
SP  - 121
EP  - 126
PB  - Science Publishing Group
SN  - 2326-9057
UR  - https://doi.org/10.11648/j.cmr.20170604.11
AB  - Ageing in men is associated with increased prevalence of cardiovascular risk factors and benign prostatic hyperplasia (BPH) with both entities possibly representing downstream manifestations of a common pathogenesis. There is paucity of data on the association of BPH and left ventricular hypertrophy (LVH). This study evaluated relationship between prostate volume, common cardiovascular risk factors and LVH. It was a cross sectional, prospective, hospital-based study. Thirty patients with benign prostatic enlargement (BPE) and 30 age- matched male controls without BPE were studied. All the subjects had clinical, biochemical, prostate ultrasound and echocardiographic evaluation done. SPSS IBM 20 was used to analyze data. Mean age was 65.60 ± 8.11 years (range: 54-82years). Subjects with BPE compared to those without did not significantly differ in age (66.50± 7.75 vs. 64.70±8.49; p=0.39). Significantly higher percentage of subjects with BPE had abnormally low HDL-cholesterol and high blood pressure compared with subjects without BPE. Eight (26.7%) of subjects with BPE in contrast to none of the subjects without BPE had metabolic syndrome (Chi2 = 9.231; p=0.002). Left ventricular mass index were significantly higher in subjects with BPE than in those without. None of the subjects without BPE as compared with 7 (23.3%) of subjects with BPE had echocardiographic determined LVH. Echocardiographic indices that significantly correlated with prostatic volume were: LVPWd (r=0.326, p= 0.011), IVSTd (r= 0.267, p=0.039), LVMI(r=0.308, p= 0.017), LAD (r= 0.494, p <0.0001) and AOD (r= 0.352, p= 0.006). The conclusion was that BPE is associated with increased left ventricular mass index and metabolic syndrome, mostly driven by elevated blood pressure and low serum HDL-cholesterol.
VL  - 6
IS  - 4
ER  -

Copy | Download