Context: Transbronchial needle aspiration (TBNA) is a method in which an aspirating needle is used to obtain diagnostic samples from a peribronchial or submucosal lesion through a rigid [1] or flexible bronchoscope [2]. Though it is a very useful bronchoscopic technique it still remains underutilized [3]. Aims: This study was done to evaluate the sensitivity, complication rates and factors affecting the outcome of TBNA. Settings and Design: Prospective trial of fifty two patients with mediastinal lymphadenopathy on CT scan attending Respiratory Diseases Clinic of Jawaharlal Nehru Medical College Hospital. Methods and Material: We analyzed the outcome of TBNA in fifty two patients who underwent TBNA between 2010 and 2012. Sensitivity of TBNA was calculated and factors affecting the TBNA results were analyzed. Statistical analysis used:Chi square test was used for analyzing the factors affecting TBNA results. SPSS Statistics 17.0 was used for analysis. Results: The overall sensitivity of TBNA was found to be 59.6% and it was the only diagnostic technique in 47.6% of the patients. Factors associated with diagnostic acquisition of samples were lymph node size more than 1.5 cm and the presence of indirect signs on bronchoscopy. Conclusions: The sensitivity of TBNA is high in malignant mediastinal lymphadenopathy. Complications occurred in four patients who had self limited bleeding at the site of puncture which healed spontaneously. Important factors predicting the outcome of TBNA are lymph node size and the presence of indirect signs on bronchoscopy. We would recommend this procedure for detection of metastatic lymph nodes in patients with lung cancer and also for mediastinal tubercular lymphadenopathy where diagnosis could not be achieved by less invasive methods.
Published in | American Journal of Internal Medicine (Volume 1, Issue 2) |
DOI | 10.11648/j.ajim.20130102.12 |
Page(s) | 14-20 |
Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
Copyright |
Copyright © The Author(s), 2013. Published by Science Publishing Group |
Transbronchial Needle Aspiration, Mediastinal Lymphadenopathy
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APA Style
Saxena Mukul, Bhargava Rakesh, Ahmad Ibne, Akhtar Jamal, Ahmed Zuber, et al. (2013). Role of Transbronchial Needle Aspiration in Patients with Thoracic Lymphadenopathy on CT Scan. American Journal of Internal Medicine, 1(2), 14-20. https://doi.org/10.11648/j.ajim.20130102.12
ACS Style
Saxena Mukul; Bhargava Rakesh; Ahmad Ibne; Akhtar Jamal; Ahmed Zuber, et al. Role of Transbronchial Needle Aspiration in Patients with Thoracic Lymphadenopathy on CT Scan. Am. J. Intern. Med. 2013, 1(2), 14-20. doi: 10.11648/j.ajim.20130102.12
AMA Style
Saxena Mukul, Bhargava Rakesh, Ahmad Ibne, Akhtar Jamal, Ahmed Zuber, et al. Role of Transbronchial Needle Aspiration in Patients with Thoracic Lymphadenopathy on CT Scan. Am J Intern Med. 2013;1(2):14-20. doi: 10.11648/j.ajim.20130102.12
@article{10.11648/j.ajim.20130102.12, author = {Saxena Mukul and Bhargava Rakesh and Ahmad Ibne and Akhtar Jamal and Ahmed Zuber and Shameem Mohammad and Alam Mohammed Mazhar and Ejazi Arshad and Baneen Ummul and Gaba Ankit}, title = {Role of Transbronchial Needle Aspiration in Patients with Thoracic Lymphadenopathy on CT Scan}, journal = {American Journal of Internal Medicine}, volume = {1}, number = {2}, pages = {14-20}, doi = {10.11648/j.ajim.20130102.12}, url = {https://doi.org/10.11648/j.ajim.20130102.12}, eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ajim.20130102.12}, abstract = {Context: Transbronchial needle aspiration (TBNA) is a method in which an aspirating needle is used to obtain diagnostic samples from a peribronchial or submucosal lesion through a rigid [1] or flexible bronchoscope [2]. Though it is a very useful bronchoscopic technique it still remains underutilized [3]. Aims: This study was done to evaluate the sensitivity, complication rates and factors affecting the outcome of TBNA. Settings and Design: Prospective trial of fifty two patients with mediastinal lymphadenopathy on CT scan attending Respiratory Diseases Clinic of Jawaharlal Nehru Medical College Hospital. Methods and Material: We analyzed the outcome of TBNA in fifty two patients who underwent TBNA between 2010 and 2012. Sensitivity of TBNA was calculated and factors affecting the TBNA results were analyzed. Statistical analysis used:Chi square test was used for analyzing the factors affecting TBNA results. SPSS Statistics 17.0 was used for analysis. Results: The overall sensitivity of TBNA was found to be 59.6% and it was the only diagnostic technique in 47.6% of the patients. Factors associated with diagnostic acquisition of samples were lymph node size more than 1.5 cm and the presence of indirect signs on bronchoscopy. Conclusions: The sensitivity of TBNA is high in malignant mediastinal lymphadenopathy. Complications occurred in four patients who had self limited bleeding at the site of puncture which healed spontaneously. Important factors predicting the outcome of TBNA are lymph node size and the presence of indirect signs on bronchoscopy. We would recommend this procedure for detection of metastatic lymph nodes in patients with lung cancer and also for mediastinal tubercular lymphadenopathy where diagnosis could not be achieved by less invasive methods.}, year = {2013} }
TY - JOUR T1 - Role of Transbronchial Needle Aspiration in Patients with Thoracic Lymphadenopathy on CT Scan AU - Saxena Mukul AU - Bhargava Rakesh AU - Ahmad Ibne AU - Akhtar Jamal AU - Ahmed Zuber AU - Shameem Mohammad AU - Alam Mohammed Mazhar AU - Ejazi Arshad AU - Baneen Ummul AU - Gaba Ankit Y1 - 2013/07/10 PY - 2013 N1 - https://doi.org/10.11648/j.ajim.20130102.12 DO - 10.11648/j.ajim.20130102.12 T2 - American Journal of Internal Medicine JF - American Journal of Internal Medicine JO - American Journal of Internal Medicine SP - 14 EP - 20 PB - Science Publishing Group SN - 2330-4324 UR - https://doi.org/10.11648/j.ajim.20130102.12 AB - Context: Transbronchial needle aspiration (TBNA) is a method in which an aspirating needle is used to obtain diagnostic samples from a peribronchial or submucosal lesion through a rigid [1] or flexible bronchoscope [2]. Though it is a very useful bronchoscopic technique it still remains underutilized [3]. Aims: This study was done to evaluate the sensitivity, complication rates and factors affecting the outcome of TBNA. Settings and Design: Prospective trial of fifty two patients with mediastinal lymphadenopathy on CT scan attending Respiratory Diseases Clinic of Jawaharlal Nehru Medical College Hospital. Methods and Material: We analyzed the outcome of TBNA in fifty two patients who underwent TBNA between 2010 and 2012. Sensitivity of TBNA was calculated and factors affecting the TBNA results were analyzed. Statistical analysis used:Chi square test was used for analyzing the factors affecting TBNA results. SPSS Statistics 17.0 was used for analysis. Results: The overall sensitivity of TBNA was found to be 59.6% and it was the only diagnostic technique in 47.6% of the patients. Factors associated with diagnostic acquisition of samples were lymph node size more than 1.5 cm and the presence of indirect signs on bronchoscopy. Conclusions: The sensitivity of TBNA is high in malignant mediastinal lymphadenopathy. Complications occurred in four patients who had self limited bleeding at the site of puncture which healed spontaneously. Important factors predicting the outcome of TBNA are lymph node size and the presence of indirect signs on bronchoscopy. We would recommend this procedure for detection of metastatic lymph nodes in patients with lung cancer and also for mediastinal tubercular lymphadenopathy where diagnosis could not be achieved by less invasive methods. VL - 1 IS - 2 ER -