Otorhinolaryngologie Alterations in Patients with Gastro-Esophageal Reflux Diseases

Mariana Penkova Radicheva

doi:doi:10.11648/j.sjcm.20140302.14

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Otorhinolaryngologie Alterations in Patients with Gastro-Esophageal Reflux Diseases

Mariana Penkova Radicheva

Published in Science Journal of Clinical Medicine (Volume 3, Issue 2)

Received: 26 March 2014 Accepted: 22 April 2014 Published: 30 April 2014

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Abstract

Introduction: The gastroesophageal reflux disease (GERD) is defined as a chronic affection resulting from the reflux of part of the gastric content (and sometimes, gastroduodenal) to the esophagus and/or adjacent organs (pharynx, larynx, bronchia), causing a variable spectrum of esophageal and/or extra-esophageal signs and symptoms associated or not to tissue lesions. Object: To determine the prevalence of ORL’ disorders in patients with gastro-esophageal reflux disease (GERD). Nowadays the number of patients with such complaints increases, which could be a result of higher acidity, inappropriate eating and lifestyle. Material and Methods: We carried out a retrospective study by approaching records of 54 patients attended in a period of 18 months. For all patients were made: standard ORL’ examination; examinations of gastro-digestive tract: upper endoscopy (Patients with erosive esophagitis were classified according to the criteria of Los Angeles), X- Ray of esophagus and stomach; Ph test; The results were evaluated in the SPSS program, version 10.0, and we carried out frequencies evaluation, central tendency and standard deviation measurements and association test (chi-square). Results: Patients with typical symptoms of gastroesophageal reflux disease accounted for 48 (88%) .Twenty seven had changes consistent with class A (50%), class B with 17 (31.5%) and 10 with classes C + D (18.5%). The presence of laryngeal changes were more prevalent in more severe esophagitis (grades C and D Los Angeles) when compared to milder forms (classes A and B), a statistically significant difference (p<0.05). Conclusion: As a first level of gastro-digestive tract, the oral cavity can attack with hirer PH of stomach’ contents. Following these circumstances they are possible changes and lesions in the mucosa of oral cavity and the pharynx wall, the tongue root and teeth. The laryngeal disorders are frequent findings in patients with GERD, more frequent the greater the degree of esophageal injury.

Published in	Science Journal of Clinical Medicine (Volume 3, Issue 2)
DOI	10.11648/j.sjcm.20140302.14
Page(s)	29-32
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Gastro-Esophageal Reflux Diseases (GERD), GERD Symptoms, Chronic Laryngitis, Oral Cavity, Gastroduodenal Reflux

References

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[2]	Farrokhi F, Vaezi MF. Extra-esophageal manifestions of gastroesophageal reflux. Oral Diseases. 2001, 13:349-59.
[3]	Ulualp SO, Toohill RJ, Shaker R. Outcomes of acid supressive therapy in patients with posterior laryngitis. Otolaryngol Head Neck Surg. 2001, 124:16-22.
[4]	Ford CN. Evaluation and Management of Laryngopharyngeal Reflux. Jama. 2005, 294(12):1534-1540.
[5]	Toros et al. Association of laryngopharyngeal manifestions and gastroesophageal reflux. Eur Arch Otorhinolaryngol. 2009, 266:403-9.
[6]	Barbuti RC, Moraes-Filho JPP. Doença do Refluxo Gastroesofágico. Gastroenterologia Medsi. 2004, 119-128.
[7]	Dent J. et al. An evid.ence-based appraisal of reflux disease management - the Genval Workshop Report. GUT. 1999, 44(2):S1-S16.
[8]	Pribuisene R, Uloza V, Jonaitis L. Typical and atypical symptoms of laryngopharyngeal reflux disease. Medicina. 2002, 38(7):699-705.
[9]	Book DT, et al. Perspectives in laryngopharyngeal reflux: an international survey. Laryngoscope. 2002, 16:274-277.
[10]	Koufman JA. The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development os laryngeal injury. Laryngoscope. 1991, 101:01-78.
[11]	Vaezi MF. Laryngitis and gastroesophageal reflux disease: increasing prevalence or poor diagnostic tests? Am J Gastroenterol. 2004, 99:1000-1010.
[12]	Ylitalo R, Lindestad P, Ramel S. Symptoms, laryngeal findings, and 24-hour pH monitoring in patients with suspected gastroesophago-pharyngeal reflux. Laryngoscope. 2001, 111:1735-1741.
[13]	Sharma P, Vakil N. Review article: Helicobacter pylori and reflux disease. Aliment Pharmacol Ther 2003; 17: 297–305.
[14]	McColl KE. Review article: Helicobacter pylori and gastro-oesophageal reflux disease-the European perspective. Aliment Pharmacol Ther 2004; 20 (suppl 8):36–39.
[15]	Haruma K. Review article: influence of Helicobacter pylori on gastro-oesophageal reflux disease in Japan. Aliment Pharmacol Ther 2004; 20 (suppl 8):40–44.
[16]	Raghunath AS, Hungin AP, Wooff D, Childs S. Systematic review: the effect of Helicobacter pylori and its eradication on gastro-oesophageal reflux disease in patients with duodenal ulcers or reflux oesophagitis. Aliment Pharmacol Ther 2004; 20: 733–744.

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Mariana Penkova Radicheva. (2014). Otorhinolaryngologie Alterations in Patients with Gastro-Esophageal Reflux Diseases. Science Journal of Clinical Medicine, 3(2), 29-32. https://doi.org/10.11648/j.sjcm.20140302.14

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ACS Style

Mariana Penkova Radicheva. Otorhinolaryngologie Alterations in Patients with Gastro-Esophageal Reflux Diseases. Sci. J. Clin. Med. 2014, 3(2), 29-32. doi: 10.11648/j.sjcm.20140302.14

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AMA Style

Mariana Penkova Radicheva. Otorhinolaryngologie Alterations in Patients with Gastro-Esophageal Reflux Diseases. Sci J Clin Med. 2014;3(2):29-32. doi: 10.11648/j.sjcm.20140302.14

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@article{10.11648/j.sjcm.20140302.14,
  author = {Mariana Penkova Radicheva},
  title = {Otorhinolaryngologie Alterations in Patients with Gastro-Esophageal Reflux Diseases},
  journal = {Science Journal of Clinical Medicine},
  volume = {3},
  number = {2},
  pages = {29-32},
  doi = {10.11648/j.sjcm.20140302.14},
  url = {https://doi.org/10.11648/j.sjcm.20140302.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20140302.14},
  abstract = {Introduction: The gastroesophageal reflux disease (GERD) is defined as a chronic affection resulting from the reflux of part of the gastric content (and sometimes, gastroduodenal) to the esophagus and/or adjacent organs (pharynx, larynx, bronchia), causing a variable spectrum of esophageal and/or extra-esophageal signs and symptoms associated or not to tissue lesions. Object: To determine the prevalence of ORL’ disorders in patients with gastro-esophageal reflux disease (GERD). Nowadays the number of patients with such complaints increases, which could be a result of higher acidity, inappropriate eating and lifestyle. Material and Methods: We carried out a retrospective study by approaching records of 54 patients attended in a period of 18 months. For all patients were made: standard ORL’ examination; examinations of gastro-digestive tract: upper endoscopy (Patients with erosive esophagitis were classified according to the criteria of Los Angeles), X- Ray of esophagus and stomach; Ph test; The results were evaluated in the SPSS program, version 10.0, and we carried out frequencies evaluation, central tendency and standard deviation measurements and association test (chi-square). Results: Patients with typical symptoms of gastroesophageal reflux disease accounted for 48 (88%) .Twenty seven had changes consistent with class A (50%), class B with 17 (31.5%) and 10 with classes C + D (18.5%). The presence of laryngeal changes were more prevalent in more severe esophagitis (grades C and D Los Angeles) when compared to milder forms (classes A and B), a statistically significant difference (p<0.05). Conclusion: As a first level of gastro-digestive tract, the oral cavity can attack with hirer PH of stomach’ contents. Following these circumstances they are possible changes and lesions in the mucosa of oral cavity and the pharynx wall, the tongue root and teeth. The laryngeal disorders are frequent findings in patients with GERD, more frequent the greater the degree of esophageal injury.},
 year = {2014}
}

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TY  - JOUR
T1  - Otorhinolaryngologie Alterations in Patients with Gastro-Esophageal Reflux Diseases
AU  - Mariana Penkova Radicheva
Y1  - 2014/04/30
PY  - 2014
N1  - https://doi.org/10.11648/j.sjcm.20140302.14
DO  - 10.11648/j.sjcm.20140302.14
T2  - Science Journal of Clinical Medicine
JF  - Science Journal of Clinical Medicine
JO  - Science Journal of Clinical Medicine
SP  - 29
EP  - 32
PB  - Science Publishing Group
SN  - 2327-2732
UR  - https://doi.org/10.11648/j.sjcm.20140302.14
AB  - Introduction: The gastroesophageal reflux disease (GERD) is defined as a chronic affection resulting from the reflux of part of the gastric content (and sometimes, gastroduodenal) to the esophagus and/or adjacent organs (pharynx, larynx, bronchia), causing a variable spectrum of esophageal and/or extra-esophageal signs and symptoms associated or not to tissue lesions. Object: To determine the prevalence of ORL’ disorders in patients with gastro-esophageal reflux disease (GERD). Nowadays the number of patients with such complaints increases, which could be a result of higher acidity, inappropriate eating and lifestyle. Material and Methods: We carried out a retrospective study by approaching records of 54 patients attended in a period of 18 months. For all patients were made: standard ORL’ examination; examinations of gastro-digestive tract: upper endoscopy (Patients with erosive esophagitis were classified according to the criteria of Los Angeles), X- Ray of esophagus and stomach; Ph test; The results were evaluated in the SPSS program, version 10.0, and we carried out frequencies evaluation, central tendency and standard deviation measurements and association test (chi-square). Results: Patients with typical symptoms of gastroesophageal reflux disease accounted for 48 (88%) .Twenty seven had changes consistent with class A (50%), class B with 17 (31.5%) and 10 with classes C + D (18.5%). The presence of laryngeal changes were more prevalent in more severe esophagitis (grades C and D Los Angeles) when compared to milder forms (classes A and B), a statistically significant difference (p<0.05). Conclusion: As a first level of gastro-digestive tract, the oral cavity can attack with hirer PH of stomach’ contents. Following these circumstances they are possible changes and lesions in the mucosa of oral cavity and the pharynx wall, the tongue root and teeth. The laryngeal disorders are frequent findings in patients with GERD, more frequent the greater the degree of esophageal injury.
VL  - 3
IS  - 2
ER  -

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Author Information

Mariana Penkova Radicheva

Clinic of Internal Diseases, University Hospital Stara Zagora, Trakia University, Stara Zagora, Bulgaria

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Mariana Penkova Radicheva. (2014). Otorhinolaryngologie Alterations in Patients with Gastro-Esophageal Reflux Diseases. Science Journal of Clinical Medicine, 3(2), 29-32. https://doi.org/10.11648/j.sjcm.20140302.14

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ACS Style

Mariana Penkova Radicheva. Otorhinolaryngologie Alterations in Patients with Gastro-Esophageal Reflux Diseases. Sci. J. Clin. Med. 2014, 3(2), 29-32. doi: 10.11648/j.sjcm.20140302.14

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AMA Style

Mariana Penkova Radicheva. Otorhinolaryngologie Alterations in Patients with Gastro-Esophageal Reflux Diseases. Sci J Clin Med. 2014;3(2):29-32. doi: 10.11648/j.sjcm.20140302.14

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@article{10.11648/j.sjcm.20140302.14,
  author = {Mariana Penkova Radicheva},
  title = {Otorhinolaryngologie Alterations in Patients with Gastro-Esophageal Reflux Diseases},
  journal = {Science Journal of Clinical Medicine},
  volume = {3},
  number = {2},
  pages = {29-32},
  doi = {10.11648/j.sjcm.20140302.14},
  url = {https://doi.org/10.11648/j.sjcm.20140302.14},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjcm.20140302.14},
  abstract = {Introduction: The gastroesophageal reflux disease (GERD) is defined as a chronic affection resulting from the reflux of part of the gastric content (and sometimes, gastroduodenal) to the esophagus and/or adjacent organs (pharynx, larynx, bronchia), causing a variable spectrum of esophageal and/or extra-esophageal signs and symptoms associated or not to tissue lesions. Object: To determine the prevalence of ORL’ disorders in patients with gastro-esophageal reflux disease (GERD). Nowadays the number of patients with such complaints increases, which could be a result of higher acidity, inappropriate eating and lifestyle. Material and Methods: We carried out a retrospective study by approaching records of 54 patients attended in a period of 18 months. For all patients were made: standard ORL’ examination; examinations of gastro-digestive tract: upper endoscopy (Patients with erosive esophagitis were classified according to the criteria of Los Angeles), X- Ray of esophagus and stomach; Ph test; The results were evaluated in the SPSS program, version 10.0, and we carried out frequencies evaluation, central tendency and standard deviation measurements and association test (chi-square). Results: Patients with typical symptoms of gastroesophageal reflux disease accounted for 48 (88%) .Twenty seven had changes consistent with class A (50%), class B with 17 (31.5%) and 10 with classes C + D (18.5%). The presence of laryngeal changes were more prevalent in more severe esophagitis (grades C and D Los Angeles) when compared to milder forms (classes A and B), a statistically significant difference (p<0.05). Conclusion: As a first level of gastro-digestive tract, the oral cavity can attack with hirer PH of stomach’ contents. Following these circumstances they are possible changes and lesions in the mucosa of oral cavity and the pharynx wall, the tongue root and teeth. The laryngeal disorders are frequent findings in patients with GERD, more frequent the greater the degree of esophageal injury.},
 year = {2014}
}

Copy | Download

TY  - JOUR
T1  - Otorhinolaryngologie Alterations in Patients with Gastro-Esophageal Reflux Diseases
AU  - Mariana Penkova Radicheva
Y1  - 2014/04/30
PY  - 2014
N1  - https://doi.org/10.11648/j.sjcm.20140302.14
DO  - 10.11648/j.sjcm.20140302.14
T2  - Science Journal of Clinical Medicine
JF  - Science Journal of Clinical Medicine
JO  - Science Journal of Clinical Medicine
SP  - 29
EP  - 32
PB  - Science Publishing Group
SN  - 2327-2732
UR  - https://doi.org/10.11648/j.sjcm.20140302.14
AB  - Introduction: The gastroesophageal reflux disease (GERD) is defined as a chronic affection resulting from the reflux of part of the gastric content (and sometimes, gastroduodenal) to the esophagus and/or adjacent organs (pharynx, larynx, bronchia), causing a variable spectrum of esophageal and/or extra-esophageal signs and symptoms associated or not to tissue lesions. Object: To determine the prevalence of ORL’ disorders in patients with gastro-esophageal reflux disease (GERD). Nowadays the number of patients with such complaints increases, which could be a result of higher acidity, inappropriate eating and lifestyle. Material and Methods: We carried out a retrospective study by approaching records of 54 patients attended in a period of 18 months. For all patients were made: standard ORL’ examination; examinations of gastro-digestive tract: upper endoscopy (Patients with erosive esophagitis were classified according to the criteria of Los Angeles), X- Ray of esophagus and stomach; Ph test; The results were evaluated in the SPSS program, version 10.0, and we carried out frequencies evaluation, central tendency and standard deviation measurements and association test (chi-square). Results: Patients with typical symptoms of gastroesophageal reflux disease accounted for 48 (88%) .Twenty seven had changes consistent with class A (50%), class B with 17 (31.5%) and 10 with classes C + D (18.5%). The presence of laryngeal changes were more prevalent in more severe esophagitis (grades C and D Los Angeles) when compared to milder forms (classes A and B), a statistically significant difference (p<0.05). Conclusion: As a first level of gastro-digestive tract, the oral cavity can attack with hirer PH of stomach’ contents. Following these circumstances they are possible changes and lesions in the mucosa of oral cavity and the pharynx wall, the tongue root and teeth. The laryngeal disorders are frequent findings in patients with GERD, more frequent the greater the degree of esophageal injury.
VL  - 3
IS  - 2
ER  -

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