Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger

Mahamane Idi Issa Abdoulahi; Bakasso Sahabi; Alio Sanda Abdelkader; Ilagouma Amadou Tidjani; Yaou Chaïbou; Moctar Chaibou; Adamou Ibrahim Maman Laouali; Kiendrebeogo Martin; Sadou Hassimi

doi:doi:10.11648/j.jdmp.20200604.15

Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger

Mahamane Idi Issa Abdoulahi, Bakasso Sahabi, Alio Sanda Abdelkader, Ilagouma Amadou Tidjani, Yaou Chaïbou, Moctar Chaibou, Adamou Ibrahim Maman Laouali, Kiendrebeogo Martin, Sadou Hassimi

Published in Journal of Diseases and Medicinal Plants (Volume 6, Issue 4)

Received: 8 December 2020 Accepted: 16 December 2020 Published: 31 December 2020

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Abstract

Resistance phenomena of infectious agents to synthesis drugs and the high cost of these drugs led to medicinal plants as an alternative against infectious disease. The objective of this study is to characterize different classes of secondary metabolites and to test the antibacterial activity of six plants: Bauhinia rufescens Lam, Blepharis linariifolia PERS, Chrozophora brocchiana Vis, Gardenia ternifolia Schum and Thonn, Indigofera astragalina DC, Phyllanthus pentandrus Schumach &Thonn, used in traditional medicine for children treatment. The extracts are obtained by aqueous decoction with the 1/10 model (50 g of each sample in 500 ml of solvent). Phytochemical screening of these six plants was carried out by standards tests, which are reactions of colorations, precipitation and complexation. The agr medium diffusion was used for the sensitivity test of the aqueous extracts of these plants against two strains of bacteria (two isolates of Salmonella typhimurium lettuce and clinical). Phytochemical screening showed the presence of polyphenols, tannins, flavonoids, coumarins, alkaloids, sterols/triterpenes in all tested extracts. All extracts contain saponins except Phyllanthus pentandrus. For free quinones, only Phyllanthus pentandrus and Indigofera astragalina showed a negative test. Among these six plants, five (5) showed an activity on Salmonella typhimurium at 200 mg/mL. C. brocchiana and P. pentandrus showed the best activity on S. typhimurium (lettuce) with 19.5±0.70 mm and 17.5±0.70 mm, respectively. At the concentration of 50 mg/mL, only these two plants are also showed antibacterial activity on S. typhimurium (lettuce). The results obtained indicate that these plants contain some secondary metabolites, some have antimiocrobial activity and constitute a scientific database for the research in the field of phytomedicines. These results will justify the use of these plants in the treatment of some infections.

Published in	Journal of Diseases and Medicinal Plants (Volume 6, Issue 4)
DOI	10.11648/j.jdmp.20200604.15
Page(s)	92-97
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Phytochemistry, Salmonella typhimurium, Infectious Agents, Niger

References

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Mahamane Idi Issa Abdoulahi, Bakasso Sahabi, Alio Sanda Abdelkader, Ilagouma Amadou Tidjani, Yaou Chaïbou, et al. (2020). Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger. Journal of Diseases and Medicinal Plants, 6(4), 92-97. https://doi.org/10.11648/j.jdmp.20200604.15

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Mahamane Idi Issa Abdoulahi; Bakasso Sahabi; Alio Sanda Abdelkader; Ilagouma Amadou Tidjani; Yaou Chaïbou, et al. Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger. J. Dis. Med. Plants 2020, 6(4), 92-97. doi: 10.11648/j.jdmp.20200604.15

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AMA Style

Mahamane Idi Issa Abdoulahi, Bakasso Sahabi, Alio Sanda Abdelkader, Ilagouma Amadou Tidjani, Yaou Chaïbou, et al. Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger. J Dis Med Plants. 2020;6(4):92-97. doi: 10.11648/j.jdmp.20200604.15

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@article{10.11648/j.jdmp.20200604.15,
  author = {Mahamane Idi Issa Abdoulahi and Bakasso Sahabi and Alio Sanda Abdelkader and Ilagouma Amadou Tidjani and Yaou Chaïbou and Moctar Chaibou and Adamou Ibrahim Maman Laouali and Kiendrebeogo Martin and Sadou Hassimi},
  title = {Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {6},
  number = {4},
  pages = {92-97},
  doi = {10.11648/j.jdmp.20200604.15},
  url = {https://doi.org/10.11648/j.jdmp.20200604.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20200604.15},
  abstract = {Resistance phenomena of infectious agents to synthesis drugs and the high cost of these drugs led to medicinal plants as an alternative against infectious disease. The objective of this study is to characterize different classes of secondary metabolites and to test the antibacterial activity of six plants: Bauhinia rufescens Lam, Blepharis linariifolia PERS, Chrozophora brocchiana Vis, Gardenia ternifolia Schum and Thonn, Indigofera astragalina DC, Phyllanthus pentandrus Schumach &Thonn, used in traditional medicine for children treatment. The extracts are obtained by aqueous decoction with the 1/10 model (50 g of each sample in 500 ml of solvent). Phytochemical screening of these six plants was carried out by standards tests, which are reactions of colorations, precipitation and complexation. The agr medium diffusion was used for the sensitivity test of the aqueous extracts of these plants against two strains of bacteria (two isolates of Salmonella typhimurium lettuce and clinical). Phytochemical screening showed the presence of polyphenols, tannins, flavonoids, coumarins, alkaloids, sterols/triterpenes in all tested extracts. All extracts contain saponins except Phyllanthus pentandrus. For free quinones, only Phyllanthus pentandrus and Indigofera astragalina showed a negative test. Among these six plants, five (5) showed an activity on Salmonella typhimurium at 200 mg/mL. C. brocchiana and P. pentandrus showed the best activity on S. typhimurium (lettuce) with 19.5±0.70 mm and 17.5±0.70 mm, respectively. At the concentration of 50 mg/mL, only these two plants are also showed antibacterial activity on S. typhimurium (lettuce). The results obtained indicate that these plants contain some secondary metabolites, some have antimiocrobial activity and constitute a scientific database for the research in the field of phytomedicines. These results will justify the use of these plants in the treatment of some infections.},
 year = {2020}
}

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TY - JOUR
T1 - Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger
AU - Mahamane Idi Issa Abdoulahi
AU - Bakasso Sahabi
AU - Alio Sanda Abdelkader
AU - Ilagouma Amadou Tidjani
AU - Yaou Chaïbou
AU - Moctar Chaibou
AU - Adamou Ibrahim Maman Laouali
AU - Kiendrebeogo Martin
AU - Sadou Hassimi
Y1 - 2020/12/31
PY - 2020
N1 - https://doi.org/10.11648/j.jdmp.20200604.15
DO - 10.11648/j.jdmp.20200604.15
T2 - Journal of Diseases and Medicinal Plants
JF - Journal of Diseases and Medicinal Plants
JO - Journal of Diseases and Medicinal Plants
SP - 92
EP - 97
PB - Science Publishing Group
SN - 2469-8210
UR - https://doi.org/10.11648/j.jdmp.20200604.15
AB - Resistance phenomena of infectious agents to synthesis drugs and the high cost of these drugs led to medicinal plants as an alternative against infectious disease. The objective of this study is to characterize different classes of secondary metabolites and to test the antibacterial activity of six plants: Bauhinia rufescens Lam, Blepharis linariifolia PERS, Chrozophora brocchiana Vis, Gardenia ternifolia Schum and Thonn, Indigofera astragalina DC, Phyllanthus pentandrus Schumach &Thonn, used in traditional medicine for children treatment. The extracts are obtained by aqueous decoction with the 1/10 model (50 g of each sample in 500 ml of solvent). Phytochemical screening of these six plants was carried out by standards tests, which are reactions of colorations, precipitation and complexation. The agr medium diffusion was used for the sensitivity test of the aqueous extracts of these plants against two strains of bacteria (two isolates of Salmonella typhimurium lettuce and clinical). Phytochemical screening showed the presence of polyphenols, tannins, flavonoids, coumarins, alkaloids, sterols/triterpenes in all tested extracts. All extracts contain saponins except Phyllanthus pentandrus. For free quinones, only Phyllanthus pentandrus and Indigofera astragalina showed a negative test. Among these six plants, five (5) showed an activity on Salmonella typhimurium at 200 mg/mL. C. brocchiana and P. pentandrus showed the best activity on S. typhimurium (lettuce) with 19.5±0.70 mm and 17.5±0.70 mm, respectively. At the concentration of 50 mg/mL, only these two plants are also showed antibacterial activity on S. typhimurium (lettuce). The results obtained indicate that these plants contain some secondary metabolites, some have antimiocrobial activity and constitute a scientific database for the research in the field of phytomedicines. These results will justify the use of these plants in the treatment of some infections.
VL - 6
IS - 4
ER -

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Author Information

Mahamane Idi Issa Abdoulahi

Department of Chemistry, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger
Bakasso Sahabi

Department of Chemistry, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger
Alio Sanda Abdelkader

Departement of Biology, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger
Ilagouma Amadou Tidjani

Department of Chemistry, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger
Yaou Chaïbou
Moctar Chaibou

Department of Chemistry, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger
Adamou Ibrahim Maman Laouali

Departement of Biology, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger
Kiendrebeogo Martin

Life and Earth Sciences Training And Research Unit, Faculty of Science and Technology, University of Ouagadougou, Ouagadougou, Burkina Faso
Sadou Hassimi

Department of Chemistry, Faculty of Science and Technology, Abdou Moumouni University, Niamey, Niger

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Mahamane Idi Issa Abdoulahi, Bakasso Sahabi, Alio Sanda Abdelkader, Ilagouma Amadou Tidjani, Yaou Chaïbou, et al. (2020). Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger. Journal of Diseases and Medicinal Plants, 6(4), 92-97. https://doi.org/10.11648/j.jdmp.20200604.15

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Mahamane Idi Issa Abdoulahi; Bakasso Sahabi; Alio Sanda Abdelkader; Ilagouma Amadou Tidjani; Yaou Chaïbou, et al. Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger. J. Dis. Med. Plants 2020, 6(4), 92-97. doi: 10.11648/j.jdmp.20200604.15

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AMA Style

Mahamane Idi Issa Abdoulahi, Bakasso Sahabi, Alio Sanda Abdelkader, Ilagouma Amadou Tidjani, Yaou Chaïbou, et al. Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger. J Dis Med Plants. 2020;6(4):92-97. doi: 10.11648/j.jdmp.20200604.15

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@article{10.11648/j.jdmp.20200604.15,
  author = {Mahamane Idi Issa Abdoulahi and Bakasso Sahabi and Alio Sanda Abdelkader and Ilagouma Amadou Tidjani and Yaou Chaïbou and Moctar Chaibou and Adamou Ibrahim Maman Laouali and Kiendrebeogo Martin and Sadou Hassimi},
  title = {Phytochemical Investigation and Antimicrobial Activity of Six Plants Used in Children’s Ailments Treatment in Niger},
  journal = {Journal of Diseases and Medicinal Plants},
  volume = {6},
  number = {4},
  pages = {92-97},
  doi = {10.11648/j.jdmp.20200604.15},
  url = {https://doi.org/10.11648/j.jdmp.20200604.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20200604.15},
  abstract = {Resistance phenomena of infectious agents to synthesis drugs and the high cost of these drugs led to medicinal plants as an alternative against infectious disease. The objective of this study is to characterize different classes of secondary metabolites and to test the antibacterial activity of six plants: Bauhinia rufescens Lam, Blepharis linariifolia PERS, Chrozophora brocchiana Vis, Gardenia ternifolia Schum and Thonn, Indigofera astragalina DC, Phyllanthus pentandrus Schumach &Thonn, used in traditional medicine for children treatment. The extracts are obtained by aqueous decoction with the 1/10 model (50 g of each sample in 500 ml of solvent). Phytochemical screening of these six plants was carried out by standards tests, which are reactions of colorations, precipitation and complexation. The agr medium diffusion was used for the sensitivity test of the aqueous extracts of these plants against two strains of bacteria (two isolates of Salmonella typhimurium lettuce and clinical). Phytochemical screening showed the presence of polyphenols, tannins, flavonoids, coumarins, alkaloids, sterols/triterpenes in all tested extracts. All extracts contain saponins except Phyllanthus pentandrus. For free quinones, only Phyllanthus pentandrus and Indigofera astragalina showed a negative test. Among these six plants, five (5) showed an activity on Salmonella typhimurium at 200 mg/mL. C. brocchiana and P. pentandrus showed the best activity on S. typhimurium (lettuce) with 19.5±0.70 mm and 17.5±0.70 mm, respectively. At the concentration of 50 mg/mL, only these two plants are also showed antibacterial activity on S. typhimurium (lettuce). The results obtained indicate that these plants contain some secondary metabolites, some have antimiocrobial activity and constitute a scientific database for the research in the field of phytomedicines. These results will justify the use of these plants in the treatment of some infections.},
 year = {2020}
}

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