CNS anomalies are the second most frequent type of congenital anomalies. It is important to diagnose them as early as possible due to poor outcome. The aim of the study is to assess the role of magnetic resonance imaging in evaluation of congenital anomalies of central nervous system. This study included 80 pregnant women with suspected congenital CNS anomalies. All patients had been examined by 2D ultrasound and MRI. The majority of anomalies in the current study were anencephaly, hydrocephalus with aqueductal stenosis and Chiari malformation . Twenty percentage of brain anomalies was associated with meningioceles. A significant difference was detected in both aqueductal stenosis and dandy walker as regards history of consanguinity. The results were compared with post natal clinical assessment and MRI. It is concluded that fetal MRI is becoming an increasingly important tool in diagnosis of brain abnormalities suspected on the basis of family history or fetal sonography (with equivocal data), with continuing improvements in technology for better improvement of postnatal outcome. BPD = Biparietal diameter, CNS = Central nervous system, EFW = Expected fetal body weight, FL = Femur length, FOV = Field of view, MRI = Magnetic resonance imaging, N= Number, SD = Standard deviation, Ssfp= Steady-state free percession, ST= Slice thickness, TE =time of echo, TR=time of repetition, T2WI=T2 weighted image, US=ultrasound.
| Published in | International Journal of Medical Imaging (Volume 6, Issue 4) |
| DOI | 10.11648/j.ijmi.20180604.12 |
| Page(s) | 40-48 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2019. Published by Science Publishing Group |
Fetal MRI, CNS Anomalies, Congenital, Ultrasound, Prenatal
| [1] | Francine R, Pascale S, and Aline H: Congenital anomalies: prevalence and risk factors. Universal Journal of Public Health, 2014; 2(2):58-63. |
| [2] | Tercanli S and Prufer F: Fetal neurosonography : Ultrasound and magnetic resonance imaging in Competition, Ultraschall in Der Medizin. 2016; 37(6): 555-557. |
| [3] | Iles S: Normal pregnancy and antenatal care. In: Symonds EM, Symonds I, and Arulkumaran S. (Eds): Essential Obstetrics and Gynecology 3rd edition. E-Book Elsevier Health Sciences, China, 2013. P.85. |
| [4] | Wards L and Hui L RP: First and second trimester screening for fetal structural anomalies, Seminars in Fetal and Neonatal Medine, 2017; 72(2):79-90. |
| [5] | Bulas DI, Levine D, Barth RA, et al.: ACR-SPR practice parameter for the safe and optimal performance of fetal magnetic resonance imaging. Journal American College of Radiology, 2015; 22(2):33-60. |
| [6] | Hamisa M, Dabees N, Ataalla WM, et al.: Magnetic resonance imaging versus ultrasound examination in detection of prenatal fetal brain anomalies. The Egyptian Journal of Radiology and Nuclear Medicine, 2013; 44(3):665-672. |
| [7] | Van Doom M, Oude Rengerink K, Newsum EA, et al.: Added value of fetal MRI in fetuses with suspected brain abnormalities on neurosonography: The Journal of Maternal, Fetal and Neonatal Medicine. 2016; 29(8):2949-2961 |
| [8] | Wilson R, Gagnon A, Audibert F, et al: Prenatal diagnosis procedures and techniques to obtain a diagnostic fetal specimen or tissue: maternal and fetal risks and benefits. Journal of Obstetrics and Gynecology Canada, 2015; 37(7):656-668. |
| [9] | AL-Najjar SAA.: Three-dimensional ultrasound in evaluation of fetal brain anomalies. Zanco Journal of Medical Sciences, 2016; 20(3): 1490-1496. |
| [10] | Van Gelder MM, Van Bennekom CM, Louik C, et al.: Maternal hypertensive disorders, antihypertensive medication use, and the risk of birth defects: a case-control study. International Journal of Obstetrics and Gynaecology. 2015;122(7):1002-1009. |
| [11] | Nasri K, Ben Fradj MK, Hamdi T, et al.: Epidemiology of neural tube defects in Tunisia, 1991-2011. Pathology Research and Practice. 2014; 210(12):944-952. |
| [12] | Liu S, Rouleau J, León JA, et al.: Impact of pre-pregnancy diabetes mellitus on congenital anomalies, Journal mandate. Health Promotion and Chronic Disease Prevention in Canada. 2015;35(5):79-84. |
| [13] | El Hamid AAA, Ismail GM, Eswi AS, et al.: Fetal congenital anomalies among consanguineous and non-consanguineous marriage pregnant mothers attending Cairo university hospitals. Egyptian Nursing Journal, 2015; 10(1):1-15. |
| [14] | Eman AH and Abd-Manaf MH: Prevalence and Risk Factors for Major Congenital Anomalies among Egyptian Women: A Four-Year Study. The Medical Journal of Cairo University.2013; 81,(1), 757-762 |
| [15] | Laharwal MA, Sarmast AH, Ramzan AU, et al.: Epidemiology of the neural tube defects in Kashmir Valley. Journal of Pediatric Neurosciences. 2016;11(3):213-218. |
| [16] | Gedikbaşı A, Gül A, Oztarhan K, et al.: Termination of pregnancy and reasons for delayed decisions. Journal of Turkish German Gynecology Association. 2010;11(1):1-7. |
| [17] | Feriha HC, Hajrija M, Sajra U, et al: congenital Malformations of the Central nervous system: Clinical Approach. Bosnian journal of basic medical sciences. 2008; 8 (4): 357-360 |
| [18] | Sarkar S, Patra C, Dasgupta MK, et al.: Prevalence of congenital anomalies in neonates and associated risk factors in a tertiary care hospital in eastern India. Journal Clinical Neonatology, 2013; 2(3):131-134 |
| [19] | Dashe WO, Hernandez-Diaz S, Arbogast PG, et al.: Major congenital malformations after first trimester exposure to ACE inhibitors. The New England Journal of Medicine. 2006;354(23):2443–2451. |
| [20] | Aberg A, Westbom L. and Kallen B.: Congenital malformations among infants whose mothers had gestational diabetes or pre-existing diabetes. Early Human Development. 2001;61(2):85–95. |
| [21] | Behairy NH And Talaat S: Fetal Neurosonography: Ultrasound Findings in Different Types, Associated Syndromes and Impact on Fetal Outcome .The Medical Journal of Cairo University. 2012; 80(1): 605-611. |
| [22] | Bosemani T, Orman G, Boltshauser E, et al.: Congenital abnormalities of the posterior fossa. Radiographic, 2015; 35:200–220. |
| [23] | Hosny IA and Elghawabi HS: Ultrafast MRI of the fetus: an increasingly important tool in prenatal diagnosis of congenital anomalies. Magnetic Resonance Imaging, 2010; 28(10):1431-1439. |
APA Style
Alaa Mohamed Reda, Rania Essam-El-Dein Mohamed Ali, Hesham Abdel Aziz Salem, Khaled Esmail El-Shafey. (2019). Added Value of Fetal Magnetic Resonance Imaging in Diagnosis of Central Nervous System Congenital Anomalies in Egyptian Population. International Journal of Medical Imaging, 6(4), 40-48. https://doi.org/10.11648/j.ijmi.20180604.12
ACS Style
Alaa Mohamed Reda; Rania Essam-El-Dein Mohamed Ali; Hesham Abdel Aziz Salem; Khaled Esmail El-Shafey. Added Value of Fetal Magnetic Resonance Imaging in Diagnosis of Central Nervous System Congenital Anomalies in Egyptian Population. Int. J. Med. Imaging 2019, 6(4), 40-48. doi: 10.11648/j.ijmi.20180604.12
AMA Style
Alaa Mohamed Reda, Rania Essam-El-Dein Mohamed Ali, Hesham Abdel Aziz Salem, Khaled Esmail El-Shafey. Added Value of Fetal Magnetic Resonance Imaging in Diagnosis of Central Nervous System Congenital Anomalies in Egyptian Population. Int J Med Imaging. 2019;6(4):40-48. doi: 10.11648/j.ijmi.20180604.12
Share This Article
Twitter
Linked In
Facebook
Copy
Download@article{10.11648/j.ijmi.20180604.12,
author = {Alaa Mohamed Reda and Rania Essam-El-Dein Mohamed Ali and Hesham Abdel Aziz Salem and Khaled Esmail El-Shafey},
title = {Added Value of Fetal Magnetic Resonance Imaging in Diagnosis of Central Nervous System Congenital Anomalies in Egyptian Population},
journal = {International Journal of Medical Imaging},
volume = {6},
number = {4},
pages = {40-48},
doi = {10.11648/j.ijmi.20180604.12},
url = {https://doi.org/10.11648/j.ijmi.20180604.12},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijmi.20180604.12},
abstract = {CNS anomalies are the second most frequent type of congenital anomalies. It is important to diagnose them as early as possible due to poor outcome. The aim of the study is to assess the role of magnetic resonance imaging in evaluation of congenital anomalies of central nervous system. This study included 80 pregnant women with suspected congenital CNS anomalies. All patients had been examined by 2D ultrasound and MRI. The majority of anomalies in the current study were anencephaly, hydrocephalus with aqueductal stenosis and Chiari malformation . Twenty percentage of brain anomalies was associated with meningioceles. A significant difference was detected in both aqueductal stenosis and dandy walker as regards history of consanguinity. The results were compared with post natal clinical assessment and MRI. It is concluded that fetal MRI is becoming an increasingly important tool in diagnosis of brain abnormalities suspected on the basis of family history or fetal sonography (with equivocal data), with continuing improvements in technology for better improvement of postnatal outcome. BPD = Biparietal diameter, CNS = Central nervous system, EFW = Expected fetal body weight, FL = Femur length, FOV = Field of view, MRI = Magnetic resonance imaging, N= Number, SD = Standard deviation, Ssfp= Steady-state free percession, ST= Slice thickness, TE =time of echo, TR=time of repetition, T2WI=T2 weighted image, US=ultrasound.},
year = {2019}
}
TY - JOUR T1 - Added Value of Fetal Magnetic Resonance Imaging in Diagnosis of Central Nervous System Congenital Anomalies in Egyptian Population AU - Alaa Mohamed Reda AU - Rania Essam-El-Dein Mohamed Ali AU - Hesham Abdel Aziz Salem AU - Khaled Esmail El-Shafey Y1 - 2019/01/23 PY - 2019 N1 - https://doi.org/10.11648/j.ijmi.20180604.12 DO - 10.11648/j.ijmi.20180604.12 T2 - International Journal of Medical Imaging JF - International Journal of Medical Imaging JO - International Journal of Medical Imaging SP - 40 EP - 48 PB - Science Publishing Group SN - 2330-832X UR - https://doi.org/10.11648/j.ijmi.20180604.12 AB - CNS anomalies are the second most frequent type of congenital anomalies. It is important to diagnose them as early as possible due to poor outcome. The aim of the study is to assess the role of magnetic resonance imaging in evaluation of congenital anomalies of central nervous system. This study included 80 pregnant women with suspected congenital CNS anomalies. All patients had been examined by 2D ultrasound and MRI. The majority of anomalies in the current study were anencephaly, hydrocephalus with aqueductal stenosis and Chiari malformation . Twenty percentage of brain anomalies was associated with meningioceles. A significant difference was detected in both aqueductal stenosis and dandy walker as regards history of consanguinity. The results were compared with post natal clinical assessment and MRI. It is concluded that fetal MRI is becoming an increasingly important tool in diagnosis of brain abnormalities suspected on the basis of family history or fetal sonography (with equivocal data), with continuing improvements in technology for better improvement of postnatal outcome. BPD = Biparietal diameter, CNS = Central nervous system, EFW = Expected fetal body weight, FL = Femur length, FOV = Field of view, MRI = Magnetic resonance imaging, N= Number, SD = Standard deviation, Ssfp= Steady-state free percession, ST= Slice thickness, TE =time of echo, TR=time of repetition, T2WI=T2 weighted image, US=ultrasound. VL - 6 IS - 4 ER -
Email: